Disclaimer:
VERSO® is not affiliated with any of the below referenced studies. The authors of these studies are not affiliated with VERSO®.
- A clinical trial using resveratrol promoted caloric restriction-like effects by improving circulating glucose, insulin, and triglyceride concentrations compared to placebo: Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
- When people with non-alcoholic fatty liver disease took resveratrol as a dietary supplement for 3 months, they decreased their serum LDL levels, decreased hepatic steatosis, decreased inflammation markers such as NF-κB and, improved insulin sensitivity: Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease & Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: A randomized controlled trial
- When people who had a heart attack took resveratrol daily for 3 months, they significantly decreased their LDLc and improved both left ventricle diastolic function and endothelial function: Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease
- When healthy patients took resveratrol, they decreased oxidative and inflammatory stress: Anti-inflammatory and Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol
- Resveratrol has shown to reduce neuronal inflammation and improve cognitive performance by mitigating hallmarks of Alzheimer’s: Neuroprotective effects of resveratrol in Alzheimer disease pathology
- Healthy adults aged 50-75 years, who took resveratrol every day for 26 weeks improved their ability to complete memory tasks: Effects of Resveratrol on Memory Performance, Hippocampal Functional Connectivity, and Glucose Metabolism in Healthy Older Adults
- Patients diagnosed with Alzheimer’s who took resveratrol every day for 13 weeks saw improvements in mental examination status scores, improved cerebrospinal fluid amyloid-beta levels, and lowered cerebrospinal fluid matrix metalloproteinase 9 (mediator of neuroinflammation): Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
- In vivo rodent studies have shown that resveratrol could be used for potential treatment of pancreatic, prostate, colorectal, liver, and breast cancer: Resveratrol and cancer: focus on in vivo evidence
- In 2 clinical studies, the use of resveratrol showed promising results for cancer treatment. Results with resveratrol treatment included reduced IGF-1, which is associated with tumor formation and metastasis, and increased carcinogen-detoxifying enzymes, like glutathione S-transferase and glucuronosyltransferase: Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study & Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis
- Resveratrol activates SIRT1 and mimics effects of calorie restriction. Resveratrol treatment in multiple organisms such as yeast, worms, and fish has shown to increase longevity: Review Lifespan and healthspan extension by resveratrol & Resveratrol as a calorie restriction mimetic: therapeutic implications
- A study where mice were given a high-fat diet, along with resveratrol supplementation showed 31% reduced risk of death and had similar physiology to mice fed a standard diet without resveratrol: Resveratrol improves health and survival of mice on a high-calorie diet
- Resveratrol induces autophagy independent of SIRT1 by inhibiting mTOR activity, a key regulator of autophagy: Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
- Resveratrol has been shown to increase NAD+ and SIRT1 by inhibiting cyclic-AMP phosphodiesterase: Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
- Resveratrol and pterostilbene exhibit potent antiviral properties against SARS-CoV-2 in vitro: Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Infection In Vitro
- A collection and analysis of studies on Resveratrol and other polyphenols that demonstrate powerful anti-viral properties, and how they may be useful for combating COVID-19: New intriguing possibility for prevention of coronavirus pneumonitis: Natural purified polyphenols
- Resveratrol strongly inhibited the replication of influenza virus in MDCK cells, and significantly improved survival and decreased pulmonary viral titers in influenza virus-infected mice: Inhibition of influenza A virus replication by resveratrol
- Resveratrol and procyanidin may be a promising strategy to support treatments for the reduction of skin wrinkling, as well as reducing systemic and skin oxidative stress: Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study
