Studies on Resveratrol

Studies on Resveratrol

Disclaimer:
VERSO® is not affiliated with any of the below referenced studies. The authors of these studies are not affiliated with VERSO®.
  1. A clinical trial using resveratrol promoted caloric restriction-like effects by improving circulating glucose, insulin, and triglyceride concentrations compared to placebo: Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
  2. When people with non-alcoholic fatty liver disease took resveratrol as a dietary supplement for 3 months, they decreased their serum LDL levels, decreased hepatic steatosis, decreased inflammation markers such as NF-κB and, improved insulin sensitivity: Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease & Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: A randomized controlled trial
  3. When people who had a heart attack took resveratrol daily for 3 months, they significantly decreased their LDLc and improved both left ventricle diastolic function and endothelial function: Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease
  4. When healthy patients took resveratrol, they decreased oxidative and inflammatory stress: Anti-inflammatory and Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol
  5. Resveratrol has shown to reduce neuronal inflammation and improve cognitive performance by mitigating hallmarks of Alzheimer’s: Neuroprotective effects of resveratrol in Alzheimer disease pathology
  6. Healthy adults aged 50-75 years, who took resveratrol every day for 26 weeks improved their ability to complete memory tasks: Effects of Resveratrol on Memory Performance, Hippocampal Functional Connectivity, and Glucose Metabolism in Healthy Older Adults
  7. Patients diagnosed with Alzheimer’s who took resveratrol every day for 13 weeks saw improvements in mental examination status scores, improved cerebrospinal fluid amyloid-beta levels, and lowered cerebrospinal fluid matrix metalloproteinase 9 (mediator of neuroinflammation): Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
  8. In vivo rodent studies have shown that resveratrol could be used for potential treatment of pancreatic, prostate, colorectal, liver, and breast cancer: Resveratrol and cancer: focus on in vivo evidence
  9. In 2 clinical studies, the use of resveratrol showed promising results for cancer treatment. Results with resveratrol treatment included reduced IGF-1, which is associated with tumor formation and metastasis, and increased carcinogen-detoxifying enzymes, like glutathione S-transferase and glucuronosyltransferase: Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study & Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis
  10. Resveratrol activates SIRT1 and mimics effects of calorie restriction. Resveratrol treatment in multiple organisms such as yeast, worms, and fish has shown to increase longevity: Review Lifespan and healthspan extension by resveratrol & Resveratrol as a calorie restriction mimetic: therapeutic implications
  11. A study where mice were given a high-fat diet, along with resveratrol supplementation showed 31% reduced risk of death and had similar physiology to mice fed a standard diet without resveratrol: Resveratrol improves health and survival of mice on a high-calorie diet
  12. Resveratrol induces autophagy independent of SIRT1 by inhibiting mTOR activity, a key regulator of autophagy: Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
  13. Resveratrol has been shown to increase NAD+ and SIRT1 by inhibiting cyclic-AMP phosphodiesterase: Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
  14. Resveratrol and pterostilbene exhibit potent antiviral properties against SARS-CoV-2 in vitro: Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Infection In Vitro
  15. A collection and analysis of studies on Resveratrol and other polyphenols that demonstrate powerful anti-viral properties, and how they may be useful for combating COVID-19: New intriguing possibility for prevention of coronavirus pneumonitis: Natural purified polyphenols
  16. Resveratrol strongly inhibited the replication of influenza virus in MDCK cells, and significantly improved survival and decreased pulmonary viral titers in influenza virus-infected mice: Inhibition of influenza A virus replication by resveratrol
  17. Resveratrol and procyanidin may be a promising strategy to support treatments for the reduction of skin wrinkling, as well as reducing systemic and skin oxidative stress: Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study
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