Boost your NAD+ with NMN & Resveratrol

NMN-administered mice showed higher food intake but lower body weight compared to control mice during the process of aging. This was achieved because NMN enhanced their energy metabolism.
DOI:10.1016/j.cmet.2016.09.013

A clinical trial using resveratrol increased energy metabolism in obese humans.
DOI:https://doi.org/10.1016/j.cmet.2011.10.002

Resveratrol induces autophagy independent of SIRT1 by inhibiting mTOR activity, a key regulator of autophagy.
DOI: https://doi.org/10.1038/srep21772

30 days of resveratrol supplementation in obese humans resulted in improved mitochondrial metabolism through the AMPK-SIRT1-PGC-1α axis.
DOI: https://doi.org/10.1016/j.cmet.2011.10.002

Dietary administration of NMN in a long-term rodent study improved mitochondrial function.
DOI: https://doi.org/10.1016/j.cmet.2016.09.013

Mice with Alzheimer’s disease were given NMN every other day for 28 days and showed improved brain mitochondria respiratory capacity.
DOI: https://doi.org/10.1186/s12883-015-0272-x

Healthy adults aged 50-75 years, who took resveratrol every day for 26 weeks improved their ability to complete memory tasks.
DOI: https://doi.org/10.1523/JNEUROSCI.0385-14.2014

Resveratrol has shown to reduce neuronal inflammation and improve cognitive performance by mitigating hallmarks of Alzheimer’s.
DOI: https://doi.org/10.3389/fnagi.2014.00218

NMN Restores Brain Function by Improving Neurovascular Coupling NMN shows to have cerebral microvascular protective effects in aged mice and findings pose the question of NMN as a potential therapy to prevent aged-induced vascular cognitive impairment
DOI: https://doi.org/10.1016/j.redox.2019.101192

When people who had a heart attack took resveratrol daily for 3 months, they significantly decreased their LDLc and improved both left ventricle diastolic function and endothelial function
DOI: 10.3233/CH-2011-1424

NMN given to mice reversed mitochondrial protein hyperacetylation and delayed development of heart failure.
DOI: https://doi.org/10.1161/CIRCULATIONAHA.116.022495

Resveratrol tricks the body into thinking it’s fasting by activating the same pathways that are turned on when one is fasted. A clinical trial using resveratrol promoted caloric restriction-like effects by improving circulating glucose, insulin, and triglyceride concentrations compared to placebo
DOI:https://doi.org/10.1016/j.cmet.2011.10.002

NMN administered to COVID-19 infected patients boosts NAD+ to improve antiviral defense systems and ability to optimally control inflammation.
Huizenga, Robert, Dramatic Clinical Improvement in Nine Consecutive Acutely Ill Elderly COVID-19 Patients Treated with a Nicotinamide Mononucleotide Cocktail: A Case Series (August 17, 2020).

A collection and analysis of studies on Resveratrol and other polyphenols that demonstrate powerful anti-viral properties, and how they may be useful for combating COVID-19.
doi: 10.1111/odi.13518

Resveratrol strongly inhibited the replication of influenza virus in MDCK cells, and significantly improved survival and decreased pulmonary viral titers in influenza virus-infected mice.
doi: 10.1086/429694

Resveratrol and pterostilbene exhibit potent antiviral properties against SARS-CoV-2 in vitro.
doi: https://doi.org/10.1101/2020.09.24.285940