NAD+ levels decrease with age (~50% every 20 years) and these levels are directly correlated with a number of age-related conditions and neurodegenerative disease. A decline in NAD+ results in a decrease in energy metabolism, weakened DNA repair, and inefficient immune activation. Sirtuins, a class of longevity enzymes that regulate and control genes rely on NAD+ to guide them to do their functions. Consequently, as levels decline, sirtuins aren’t optimally guided to do their jobs to repair and maintain the body for peak health and performance. If there isn't enough NAD+ to guide sirtuins to maintain cellular identity, skin cells start to act like nerve cells, nerve cells start to act like kidney cells, etc. – the body is confused. This explains why the body breaks down with old age and consequently wrinkles appear, there will be less benefit from exercise, energy levels decline, constant fatigue and compromised mitochondrial function occurs.

Cell Being is a synergistic mix of molecules that support the production of cellular energy to promote DNA repair and maintain metabolic homeostasis by increasing NAD+ levels. Formulated with the direct precursor to NAD+, which means that it converts into NAD+ in the cell. We paired this immediate precursor with potent extract from japanese knotweed because they work synergistically to further enhance sirtuin activation, amplifying the beneficial effects on cellular health. Then we added TMG (betaine) to improve methylation pathways to potentially avoid depleting methyl groups from increased NAD+ production. It has also been used primarily to optimize athletic performance and to improve heart health.